You should totally go for a story where the male lead is an atheist CEO, and he hates every second working with the female lead — a strong Muslim woman who’s also a CEO. They’re forced to collaborate on a breakthrough cancer treatment, and even though he keeps claiming he despises her, he slowly falls head over heels.
Imagine a scene where he flirts and says something like, "If falling for you was a sin, then I guess I’m already burning... but honestly, it’s worth every flame."
And she, staying true to her faith and dignity, would gently reply with something like, "Love without purpose is just desire. If it doesn’t bring me closer to my faith, then it’s not the kind of love I pray for."
Add a major twist too — rivals trying to destroy their collaboration, leading to a car accident where her car falls off a mountain. It would bring an intense, emotional cliffhanger to the first sequel!